Ozempic vs Mounjaro : Key Differences, Benefits & Side Effects

Medically Reviewed by Dr. Shamani Mendis​
Table of content

There has been a rising dialogue in Australia surrounding two medications that aim to address obesity and type 2 diabetes, which are deemed as both critical health concerns in Australia.

The two medications are Ozempic (semaglutide) and Mounjaro (tirzepatide).

In this article, we will break down the properties of both Ozempic and Mounjaro, and their respective uses, benefits, side-effects and which one may be the right choice for you.


What is Ozempic?

Ozempic is the brand name for Semaglutide, and is a form of medication that is traditionally used in the treatment of type 2 diabetes.

Ozempic imitates the GLP-1 hormone.

This hormone produced by the pancreas helps to release the needed amount of insulin needed to regulate blood sugar levels.

While this is the traditional use of Ozempic, in recent years, numerous studies have shown it to be a tool in aiding weight loss.

Subsequently, Ozempic in Australia has become a multi-beneficial medication for those battling both diabetes and obesity.

Semaglutide is prescribed as Wegovy for weight management alone.


What is Mounjaro?

Mounjaro, known medically as Tirzepatide, is another medication that has been used to help treat people with type 2 diabetes, and help target weight loss.

Like Ozempic, Mounjaro also mimics the actions of the hormone called GLP-1.

In addition to this, Mounjaro also activates the GIP receptors.

This dual-action ability of Mounjaro, means it is an excellent tool in helping to improve blood sugar levels, fuel insulin production, reduce glucose production and promote weight loss.


What are the potential side effects of Ozempic and Mounjaro?

Ozempic and Mounjaro, just like any medication can incur side effects.

Some are more common than others, which are listed below :

  • Diarrhea
  • Nausea and Vomiting
  • Constipation
  • Headaches
  • Abdominal Pain
  • Acid Reflux
  • Gas and Bloating

There are also several less common side effects that have been reported from the use of both Ozempic and Mounjaro :

  • Pancreatitis
  • Changes in vision
  • Hypoglycemia (low blood sugar levels)
  • Allergic Reactions
  • Gallbladder problems
  • Severe dehydration leading to kidney problems
  • Low mood

If considering either options, make sure you discuss the potential side effects with your healthcare provider to understand the risks that can come from using these medications.

When starting any new medication, it is always important to consider these factors and consult with a relevant professional.


What are the main differences between Ozempic and Mounjaro?

While at their core both Ozempic and Mounjaro have similar properties and uses, there are several different factors that make them differ from one another.


How do they work on the body?

  • Ozempic’s main effect on the body is in its ability to mimic the GLP-1 hormone. Ozempic helps to slow the speed of food travelling through your digestive tract, which can help you to feel fuller for longer.
  • Mounjaro on the other hand is dual-acting imitating both the GLP-1 hormone but also the GIP hormone. It is the only medication to currently do this.
  • The dual-action compound of Mounjaro slows stomach emptying, which results in the similar feeling of fullness, and subsequent appetite suppression.
  • Both help to aid in the management of type 2 diabetes but can also help to fuel weight loss.


Which one is more effective?

  • Both studies of Ozempic and Mounjaro have shown abilities to sufficiently aid in the treatment of type 2 diabetes and potential weight loss.
  • However, in clinical trials, Mounjaro has been seen to be more effective in its ability to regulate blood sugar control and promote weight loss.
  • Ozempic have been observed to lower the potential major cardiovascular events such as a heart attack or stroke, and other heart related deaths in patients with type 2 diabetes.
  • Mounjaro has been observed to reduce A1C, a blood test that reveals your average blood glucose levels over a three month period.
  • This edge of effectiveness for Mounjaro can largely be credited to its dual action nature.


How do you take Ozempic and Mounjaro?

Both Ozempic and Mounjaro are available in a variety of different dosages.

Both are available in the form of a multi use pen device which is self administered as a subcutaneous injection on a weekly basis.


Is it more effective if injected into a certain area?

No research suggests that Ozempic or Mounjaro is more effective if injected into a specific body part.

Both absorb well into your body, no matter if it’s injected into your stomach, thigh, or abdomen.

You should always follow the instructions of a medical professional.


Can I combine Ozempic and Mounjaro?

It is not advised to mix both Ozempic and Mounjaro due to overlapping active ingredients which can result in potentially harmful side effects.


What is the cost and availability in Australia?

Both Ozempic and Mounjaro have been approved by the TGA.

The cost of Ozempic and Mounjaro can vary depending on personal circumstances, as well as the pharmacy you acquire it from.

  • Mounjaro : The approximate cost per month for Mounjaro is $280 to $700 depending on the dose.
  • Ozempic : Available on PBS for patients with type 2 diabetes
  • Wegovy : The approximate cost per month for Wegovy is $250 to $370 depending on the dose.

Whilst there has been a shortage of some of these medications in the past, there is no ongoing issue with supply.

In Australia, both the compounded formulation of Ozempic and oral form are banned.

A prescription is required from your doctor to purchase these medications.


Why pick Healthy Weight Australia?

Healthy Weight Australia offers comprehensive and personalised weight management solutions, including both non-surgical and surgical options.

Here’s why you might choose Healthy Weight Australia.

  • Expertise : The team consists of experienced healthcare professionals specialised in weight management and metabolic health.
  • Personalised Care : Each patient, in conjunction with our healthcare team will be guided by a treatment plan based on their unique health needs and goals.
  • Comprehensive Support : Patients have access to a range of services, including dietary advice, exercise plan , and follow-up care.
  • Cutting-Edge Technology : Healthy Weight Australia uses the latest technology and techniques to ensure the best outcomes for patients.
  • Holistic Approach : The focus is not just on weight loss but an overall health improvement, addressing underlying issues like diabetes, hypertension, and more.

When it comes to managing obesity and type 2 diabetes in Australia. Ozempic and Mounjaro offer promising solutions with their respective benefits and side effects.

Understanding the difference between these two forms of medication can help individuals to ensure they are taking the approach that suits them and their lifestyles the most, while putting their overall health first.

Healthy Weight Australia stands out as a provider that offers a comprehensive and patient-centered approach to weight management, making it a strong choice for those seeking effective and sustainable solutions.

Contact us today to learn more.

Healthy Weight Australia

Author

We are a medical group made up of the finest Physicians, Surgeons and Allied Health professionals across Australia. Our team of experts will help you discover a program that aligns perfectly with your personal goals.

View all posts by Healthy Weight Australia

Related Articles